Magnesium Oxide: MedlinePlus Drug Information (2024)

pronounced as (mag nee' zee um) (ox' ide)

  • Why is this medication prescribed?
  • How should this medicine be used?
  • Other uses for this medicine
  • What special precautions should I follow?
  • What should I do if I forget a dose?
  • What side effects can this medication cause?
  • What should I know about storage and disposal of this medication?
  • In case of emergency/overdose
  • What other information should I know?
  • Brand names

Why is this medication prescribed?

Magnesium is an element your body needs to function normally. Magnesium oxide may be used for different reasons. Some people use it as an antacid to relieve heartburn, sour stomach, or acid indigestion. Magnesium oxide also may be used as a laxative for short-term, rapid emptying of the bowel (before surgery, for example). It should not be used repeatedly. Magnesium oxide also is used as a dietary supplement when the amount of magnesium in the diet is not enough. Magnesium oxide is available without a prescription.

How should this medicine be used?

Magnesium oxide comes as a tablet and capsule to take by mouth. It usually is taken one to four times daily depending on which brand is used and what condition you have. Follow the directions on the package or on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take magnesium oxide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Take any other medicine and magnesium oxide at least 2 hours apart.

If you are using magnesium oxide as a laxative, take it with a full glass (8 ounces [240 milliliters]) of cold water or fruit juice. Do not take a dose late in the day on an empty stomach.

Do not take magnesium oxide as an antacid for longer than 2 weeks unless your doctor tells you to. Do not take magnesium oxide as a laxative for more than 1 week unless your doctor tells you to.

Other uses for this medicine

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking magnesium oxide,

  • tell your doctor and pharmacist if you are allergic to magnesium oxide, other antacids or laxatives, or any other drugs.
  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other antacids or laxatives, anticoagulants ('blood thinners') such as warfarin (Coumadin), aspirin, diuretics ('water pills'), medicine for ulcers (cimetidine [Tagamet], ranitidine [Zantac]), and vitamins.
  • tell your doctor if you have or have ever had heart, kidney, liver, or intestinal disease or high blood pressure.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking magnesium oxide, call your doctor immediately.
  • tell your doctor if you are on a low-salt, low-sugar, or other special diet.

What should I do if I forget a dose?

If you are taking magnesium oxide on a regular schedule, take the missed dose as soon you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Magnesium oxide may cause side effects. To avoid unpleasant taste, take the tablet with citrus fruit juice or carbonated citrus drink. Tell your doctor if either of these symptoms are severe or do not go away:

  • cramping
  • diarrhea

If you experience any of the following symptoms, call your doctor immediately:

  • rash or hives
  • itching
  • dizziness or lightheadedness
  • mood or mental changes
  • unusual tiredness
  • weakness
  • nausea
  • vomiting

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of emergency/overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

What other information should I know?

If this medicine has been prescribed for you, keep all appointments with your doctor so that your response to magnesium can be checked.

Do not let anyone else take your medicine.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names

  • Mag-Ox®
  • Maox®
  • Uro-Mag®
Last Revised - 10/15/2015

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Magnesium Oxide: MedlinePlus Drug Information (2024)

FAQs

Magnesium Oxide: MedlinePlus Drug Information? ›

Some people use it as an antacid to relieve heartburn, sour stomach, or acid indigestion. Magnesium oxide also may be used as a laxative for short-term, rapid emptying of the bowel (before surgery, for example). It should not be used repeatedly.

Why avoid magnesium oxide? ›

High doses of magnesium oxide may cause dangerously high blood magnesium levels, which is more likely in specific populations. It may also cause side effects like bloating and diarrhea and reduce the effectiveness of certain medications.

Why do doctors recommend magnesium oxide? ›

Magnesium oxide is one of the most common forms of magnesium used in dietary supplements. Though it has a poor absorption rate, studies show that taking magnesium oxide supplements may help improve symptoms of constipation, ease headaches, reduce blood pressure and blood sugar, and ease anxiety symptoms.

What drugs should not be taken with magnesium oxide? ›

What other drugs will affect magnesium oxide?
  • an antibiotic;
  • a diuretic or "water pill";
  • penicillamine;
  • a blood thinner --warfarin, Coumadin, Jantoven; or.
  • medicine to treat osteoporosis or Paget's disease --alendronate, ibandronate, risedronate, Fosamax, Boniva, Actonel, and others.

Is it okay to take magnesium oxide every day? ›

Typically, magnesium oxide should only be taken at the prescribed dose for short periods of time — no more than 2 weeks if you are using it as an antacid or 1 week if you are using it as a laxative. Potential side effects of short-term use. Potential side effects of short-term use include stomach cramping and diarrhea.

Is magnesium oxide the worst magnesium? ›

In summary: Magnesium oxide is one of the most common forms of magnesium found in dietary supplements. While it's been shown to be helpful for certain conditions, such as headaches and constipation, it's less bioavailable than other forms of magnesium and may cause side effects like diarrhea.

What are the dangers of magnesium oxide? ›

* Magnesium Oxide can affect you when breathed in. * Breathing Magnesium Oxide can irritate the eyes and nose. * Exposure to Magnesium Oxide can cause “metal fume fever.” This is a flu-like illness with symptoms of metallic taste in the mouth, headache, fever and chills, aches, chest tightness and cough.

Why do cardiologists recommend magnesium oxide? ›

“Magnesium is an electrolyte that helps to regulate your heart rate,” says cardiologist Tamanna Singh, MD. “When you have a deficiency of electrolytes, it can make your heart speed up.” We talked with Dr.

Is 400 mg of magnesium oxide too much? ›

The maximum recommended daily dose of magnesium for adults is 420 mg for males and 350 mg for females. However, some factors may influence your required dose, such as age and health conditions. Magnesium is essential for many functions in your body , including energy metabolism and protein synthesis.

Should I take magnesium oxide in the morning or at night? ›

Therefore, magnesium supplements can be taken at any time of the day, as long as you're able to take them consistently. For some, taking supplements first thing in the morning may be easiest, while others may find that taking them with dinner or just before bed works well for them.

What vitamin should you not take with magnesium? ›

Here are supplements that don't go together—or don't go with food.
  • Magnesium and calcium. ...
  • Iron and green tea. ...
  • Vitamin C and B12. ...
  • Fat-soluble and water-soluble vitamins. ...
  • Vitamin D, vitamin K2, and other fat-soluble vitamins. ...
  • Magnesium and vitamin D3. ...
  • Copper and zinc. ...
  • Omega-3s and vitamin E.
Oct 21, 2022

What cannot be mixed with magnesium? ›

Aminoglycosides: Concomitant use with magnesium may cause neuromuscular weakness and paralysis. Antibiotics: Taking magnesium supplements may reduce the absorption of quinolone antibiotics, tetracycline antibiotics, and nitrofurantoin (Macrodandin).

Who cannot take magnesium? ›

People with diabetes, intestinal disease, heart disease, or kidney disease should not take magnesium before speaking with their health care provider.

Can you take magnesium oxide indefinitely? ›

Do not take magnesium oxide as an antacid for longer than 2 weeks unless your doctor tells you to.

Is 500 mg of magnesium oxide safe? ›

When taken in very large amounts (greater than 350 mg daily), magnesium is POSSIBLY UNSAFE. Large doses might cause too much magnesium to build up in the body, causing serious side effects including an irregular heartbeat, low blood pressure, confusion, slowed breathing, coma, and death.

Which is better to take magnesium or magnesium oxide? ›

Which One Is More Effective? Research suggests that magnesium citrate is four times more effective at raising serum magnesium levels compared to magnesium oxide. All-in-all, if you want to experience the robust health benefits of magnesium, citrate is typically the better choice.

Which is better for you magnesium or magnesium oxide? ›

Which One Is More Effective? Research suggests that magnesium citrate is four times more effective at raising serum magnesium levels compared to magnesium oxide. All-in-all, if you want to experience the robust health benefits of magnesium, citrate is typically the better choice.

Is magnesium oxide pointless? ›

Magnesium oxide is best used for digestive problems and heartburn. Magnesium oxide can also be used to supplement magnesium levels in the body, but it may not work as well as other magnesium compounds that are more readily absorbed into the bloodstream, including those you can get naturally from foods.

Who should not take magnesium? ›

People with diabetes, intestinal disease, heart disease or kidney disease should not take magnesium before speaking with their health care provider. Overdose. Signs of a magnesium overdose can include nausea, diarrhea, low blood pressure, muscle weakness, and fatigue. At very high doses, magnesium can be fatal.

What are the symptoms of low magnesium oxide? ›

What are the symptoms of magnesium deficiency?
  • low appetite.
  • nausea and vomiting.
  • fatigue and weakness.
  • muscle spasms or tremors.
  • abnormal heart rhythms.

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